How do you spell Substituted

Available Definitions:
1)  a. - Exchanged; put in the place of another.
2)  a. - Containing substitutions or replacements; having been subjected to the process of substitution, or having some of its parts replaced; as, alcohol is a substituted water; methyl amine is a substituted ammonia.
3)  n. - To put in the place of another person or thing; to exchange.